Description
NAD⁺ 500mg: Nicotinamide Adenine Dinucleotide for Cellular and Metabolic Research
NAD⁺ (Nicotinamide Adenine Dinucleotide) is an essential intracellular redox coenzyme present in all living cells and fundamental to energy metabolism, mitochondrial function, and cellular repair pathways. NAD⁺ plays a central role in oxidative phosphorylation, glycolysis, and fatty acid oxidation, as well as serving as a critical substrate for enzymes involved in DNA repair, gene expression, and cellular stress responses. NAD⁺ levels are known to decline with age and during periods of metabolic or oxidative stress. As a result, NAD⁺ has become a major focus of research into age-related cellular decline, neurobiology, metabolic dysfunction, and mitochondrial health. NAD500 is supplied as a lyophilised NAD⁺ preparation for laboratory research examining these core biological processes.
Product Summary Table
| Compound Name | NAD⁺ (Nicotinamide Adenine Dinucleotide) |
| Compound Class | Pyridine nucleotide coenzyme |
| Molecular Weight | 663.43 g/mol |
| Chemical Formula | C21H27N7O14P2 |
| Primary Biological Roles | Redox reactions, mitochondrial energy metabolism, DNA repair |
| Form | Lyophilised synthetic compound (must be reconstituted) |
| Research Vial Format | 500 mg |
| Country of Origin | Australia |
| Storage | Lyophilised: store cold and protected from light; Reconstituted: 2–8°C |
| Standard | Research Grade Purity ≥98 percent |
In Vivo Research Benefits
NAD⁺ has been extensively studied in cellular, animal, and translational research models for its foundational role in metabolic and regulatory biology.
- Support of mitochondrial energy production through electron transport chain activity.
- DNA repair facilitation via poly(ADP-ribose) polymerase (PARP) enzymes.
- Regulation of gene expression through sirtuin-dependent pathways.
- Cellular stress resistance in oxidative and metabolic challenge models.
- Neurobiological function related to neuronal energy balance and signalling.
Benefits of NAD⁺ 500mg
- Core Cellular Energy Support through redox and mitochondrial pathways.
- Longevity Research Relevance due to its role in ageing-related cellular decline.
- Neurocellular Function Investigation involving brain metabolism and resilience.
- Metabolic Regulation across glucose, lipid, and oxidative systems.
- Well Characterised Molecule with extensive foundational research history.
Studies and Additional Info
- Research on NAD⁺ decline and ageing-related metabolic dysfunction
- Studies examining sirtuin activation and gene regulation
- Mitochondrial function and oxidative phosphorylation research
- Neurobiology studies involving cellular energy balance
Disclaimer: NAD⁺ 500mg is supplied strictly for laboratory research purposes. It is not intended for human consumption or therapeutic use.
Frequently Asked Questions
What is NAD⁺ studied for?
NAD⁺ is studied for its role in cellular energy production, mitochondrial function, DNA repair, and ageing-related biological processes.
Is NAD⁺ naturally present in the body?
Yes. NAD⁺ is an endogenous coenzyme found in all living cells and is essential for metabolic function.
Why is NAD⁺ important in ageing research?
NAD⁺ levels decline with age, and this reduction has been linked to impaired mitochondrial function and cellular repair capacity.
Does NAD⁺ act directly on DNA?
NAD⁺ serves as a substrate for enzymes involved in DNA repair and chromatin regulation rather than binding DNA directly.
Is NAD⁺ approved for human use?
No. This product is supplied for laboratory research only and is not approved for human consumption.




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